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Table of Contents
Reading Tips:
For fast reading, scan through the topic headings in BOLD BLACK, important conclusions in BOLD BLUE, and "Must Know" in BOLD RED. To jump to specific sections in this article, click on the respective LINKS in the Table of Contents.
Information presented here is for general educational purposes only. Each one of us is biochemically and metabolically different. If you have a specific health concern and wish my personalized nutritional recommendation, write to me by clicking here.
There is an increase
of awareness in the role of omega-3 fatty acids. Omega-3 fatty acids
are found in fish and fish oils and aid in the prevention and management
of heart diseases. This can help reduce your risk of developing
an abnormal heartbeat; which can lead to heart problems and even sudden
death.
Greater
than half of all sudden death from cardiac causes have no history of cardiovascular
disease. In
fact, over 40% of all heart attack victim autopsies show clear coronary
vessels. Clearly, there is much more going on than the simple "cholesterol
kills" hypothesis. It is interesting to note that the
first
and most common sign of cardiovascular disease in post-menopausal women
is
death.
Yes, death.
In other words, there are no signs or symptoms.
Omega-3
fatty acids provide a range of benefits and protection for the heart and
our body.
In addition
to reducing the risk of heart disease, they also help prevent blood clotting,
heart attacks and irregular heartbeats that could lead to sudden cardiac
death. They are anti-inflammatory, and inflammation is a key initiator of
the atherosclerotic cascade leading to plaque formation and sudden death.
Omega-3 also have anti-cancer functions as we shall see.
Omega-3
fatty acids can be divided into 3 main categories -- Eicosapentaenoic Acids
(EPA), Docosahexaenoic Acids (DHA) and Alpha-Linolenic Acids;
out
of which EPA and DHA have the most beneficial effects.
EPA and DHA
are found mainly in fish oils while Alpha-Linolenic Acids are usually derived
from plant sources such as soybeans, canola, walnut and flaxseed.
DEFINITION OF OMEGA
Omega-3 fatty
acids are long-chain
polyunsaturated fatty acids
(18-22 carbon atoms in chain length) with the first of many double bonds
beginning with the third carbon atom (when counting from the methyl end
of the fatty acid molecule).
The fish-based and
fish-oil-based omega-3 polyunsaturated fatty acids (also referred to as
n-3 PUFA) consist of EPA (20 carbon atoms, 5 double bonds) and DHA (22 carbon
atoms, 6 double bonds.
Some plant foods and vegetable oils do contain varying amounts of the n-3
PUFA Alpha-Linolenic Acid (ALA), which has 18 carbon atoms and 3 double
bonds. Many vegetable oils are also rich in omega-6 fatty acids. Some examples
are Linolenic acid in corn, safflower, sunflower and soybean oils.
Non-hydrogenated Canola oil, ground flaxseed and walnuts are rich sources
of ALA.
Of
all the fatty acids in the blood including saturated, monounsaturated, and
polyunsaturated, only
the percentage of long chain omega-3 predicted fewer sudden death.
In a study of 11,323 recent survivors of heart attack, either 1 gram of
omega-3 or 300 mg of Vitamin E or both was given. The usual pharmacological
regiment and lifestyle recommendations were made. It was shown that omega-3
and not Vitamin E improved survival. After 3 months of remaining on regiment
of omega-3, patterns showed a 41% decrease in mortality, a 53% reduction
in sudden death after 4 months, and after 12 months, a 30% decrease in cardiovascular
mortality. There was also a 5% decrease in triglyceride but not total cholesterol,
HDL, or LDL cholesterol.
Other studies have shown that:
1. When comparing the Greenland Inuit
and the Dutch, the former exhibit a significantly lower death rate from
acute myocardial infarction despite only moderate differences in their blood
cholesterol levels. This is because the Inuit's diet is high in fat and
provides up to several grams of omega-3 fatty acid daily, primarily in the
form of marine mammals, wildfowl and various fish.
2. In Japan, where fish intake forms a large proportion in their diet, the
mortality rates arising from various types of heart disease is significantly
lower than other countries like North America.
3. Among the Inuit of Nunavik, the progressive increases in levels of EPA
and DHA in plasma phospholipids have been found in their dietary intakes
of these fatty acids. This is useful in lowering their risk for heart diseases.