Video Channel
Video Channel

Adrenal Fatigue Center
Empowering Sufferers Worldwide Since 2001

Call Us for Free! 626-571-1234

Watch Our Testimonials

Adrenal Fatigue Center
Empowering Sufferers Worldwide Since 2001

Watch Our Testimonials

Call Us for Free! 626-571-1234

Metabolic Syndrome
By: Michael Lam, MD, MPH

Table of Contents

Reading Tips

For fast reading, scan through the topic headings in BOLD BLACK, important conclusions in BOLD BLUE, and "Must Know" in BOLD RED. To jump to specific sections in this article, click on the respective LINKS in the Table of Contents.

Information presented here is for general educational purposes only. Each one of us is biochemically and metabolically different. If you have a specific health concern and wish my personalized nutritional recommendation, write to me by clicking here.


Those who are in the sub-clinical phase (age 35-45) and clinical phase of aging (age 45 and above) have a one in three chance of getting this syndrome and not knowing it. Perhaps the following signs are more recognizable: feeling sluggish, physically and mentally, especially after a meal. Gaining a pound here and a pound there-and having increasing difficulty losing them. Having blood pressure creep up year after year and finding that the blood cholesterol, triglycerides, and blood sugar levels are doing the same. These are all accepted signs of aging. They are also all of the symptoms of Metabolic

Metabolic Syndrome can explain why you feel lousy today -- such as being tired and fuzzy-minded. It can explain why you have high triglycerides, high cholesterol or high blood pressure, why you are feeling lousy after meals, and why you are seeing your health spin out of control without knowing why. It can also explain why you are aging faster than your peers. More importantly, Metabolic Syndrome sets the stage for catastrophic health problems, such as heart disease, diabetes, Alzheimer's, cancer, and other age-related diseases.

It is estimated that this syndrome afflicts over 60 million Americans and one in four adults over age 35. Hypercholesterolemia, cigarette smoking, hypertension, and obesity are the main culprits for the development of atherosclerotic coronary artery disease (CAD). However, these account only for half of the cases of CAD. The other pathologic processes underlying atherosclerosis remain unknown. Metabolic Syndrome may be the cause of up to fifty percent of all heart attacks. It is an epidemic of massive proportion.

How do you develop Metabolic Syndrome?

Metabolic Syndrome develops slowly over time, often over a course of 20 years or more. It is the end results from years (often decades) of taking in a modern day diet high in refined carbohydrates such as breads, starches and sweets. These foods, once taken, trigger a rapid increase in blood sugar levels, and the body responds by raising levels of insulin secretion that in turn helps to move the sugar out of the blood stream into the cells. Insulin is a hormone secreted by the pancreas. It helps the body utilize glucose (blood sugar) by binding with receptors on cells like a key would fit into a lock. Once the key - insulin - has unlocked the door of the cell, the glucose passes from the blood into the cell. Inside the cell, glucose is either used for energy or stored for future use in the form of glycogen in liver or muscle cells.

The more carbohydrates you eat, the more your pancreas releases insulin to lower the excessive blood sugar. This is especially so with simple or refined carbohydrates that are converted into sugar quickly (the high-glycemic index foods like white bread and white flour) once inside your body. While insulin levels rise and fall with each meal and is part of the normal metabolic process, chronic carbohydrate overload causes chronic insulin overload. The cells of the body, be they the muscles or the fat tissues, recognize that excessive sugar is toxic. They try to shut down the influx of sugar into the cells and therefore go through a down-regulation process to resist the command of insulin. This state is called insulin resistance. The pancreas, in response to the insulin resistance and resulting lowered transport of glucose out of the blood stream to the cell, puts out even more insulin in order to avoid too high a blood sugar level. This compensatory increase in insulin output continues until the pancreas fails to keep up. Some people produce two, three or four times the normal amount of insulin. Yet, because the cells have lost their sensitivity to insulin, they require even more of it to maintain normal glucose levels. In advanced stages of insulin resistance, when the pancreas becomes exhausted and can no longer maintain the insulin production, insulin production drops, resulting in adult onset diabetes mellitus (also called type 2 diabetes). Insulin resistance plus compensatory hyperinsulinemia is nature's way of preventing the evolution into type 2 diabetes. It is often referred to as a pre-diabetic state.

As long as there is insulin resistance, the blood sugar and blood insulin levels are both high. Over time, high blood sugar and high insulin cause a myriad of destructive damages to almost every tissue they touch. It is important to recognize while insulin resistance or high blood sugar is each bad for health on its own, it takes both insulin resistance and compensatory hyperinsulinemia, to result in the various manifestations. These manifestations represent the resultant damage and surface as a compilation of symptoms representative of multi-system dysfunction. This includes the cardiovascular system, muscular system, kidney system, reproductive system, and lipid metabolic system, just to name a few. It is called Metabolic Syndrome when the symptoms are grouped collectively in a setting of insulin resistance. It can go undetected for up to 40 years, and a family history of type 2 diabetes, CHD, or hypertension increases the risk for Metabolic Syndrome.

Message from Dr. Lam

I hope you have enjoyed reading this article. If you have areas you don't understand,
or if you have a specific health concern, feel free to write to me by clicking here.

About The Author

Michael Lam, M.D., M.P.H., A.B.A.A.M., is a western trained physician specializing in nutritional and anti-aging medicine. Dr. Lam received his Bachelor of Science degree from Oregon State University, and his Doctor of Medicine degree from the Loma Linda University School of Medicine in California. He also holds a Master’s degree in Public Health. He is board certified by the American Board of Anti-Aging Medicine where he has also served as a board examiner. Dr. Lam is a pioneer in using nontoxic, natural compounds to promote the healing of many age-related degenerative conditions. He utilizes optimum blends of nutritional supplementation that manipulate food, vitamins, natural hormones, herbs, enzymes, and minerals into specific protocols to rejuvenate cellular function.

Dr. Lam was first to coin the term, ovarian-adrenal-thyroid (OAT) hormone axis, and to describe its imbalances. He was first to scientifically tie in Adrenal Fatigue Syndrome (AFS) as part of the overall neuroendocrine stress response continuum of the body. He systematized the clinical significance and coined the various phases of Adrenal Exhaustion. He has written five books: Adrenal Fatigue Syndrome - Reclaim Your Energy and Vitality with Clinically Proven Natural Programs, The Five Proven Secrets to Longevity, Beating Cancer with Natural Medicine (Free PDF version), How to Stay Young and Live Longer, and Estrogen Dominance. In 2001, Dr. Lam established as a free, educational website on evidence-based alternative medicine for the public and for health professionals. It featured the world’s most comprehensive library on AFS. Provided free as a public service, he has answered countless questions through the website on alternative health and AFS. His personal, telephone-based nutritional coaching services have enabled many around the world to regain control of their health using natural therapies.

For More Information

For the latest Anti-Aging and Adrenal Fatigue related health issues, visit Dr. Lam at
Feel free to email Dr. Lam by clicking here if you have any questions.

Protocol Disclaimer makes no representations or warranties of any kind, expressed or implied, as to the protocol or protocols sent to your personal library (the "Protocol").

You expressly agree that your decision to follow any part of the Protocol is at your sole risk and that will not be liable for any damages of any kind arising from your use, application or interpretation of the Protocol, including, but not limited to direct, indirect, incidental, punitive, and consequential damages.

The ideas, doses, concepts and opinions expressed in the Protocol are intended to be used for educational purposes only and they are not intended to be specific medical advice specially tailored for your unique medical needs, nor is the Protocol intended to replace medical advice, nor to diagnose, prescribe or treat any disease, condition, illness or injury.

Before you decide to follow the Protocol you should check with your Physician, especially if you are pregnant, nursing, have a known medical condition, are under a physician's care, taking prescription medications and/or over-the-counter medications or have any sensitivity or allergy to certain specific dietary ingredients.

It is important that you not use the supplements recommended by the Protocol as a medical prescription to treat your specific health problem or disease without consulting with a qualified health care provider or licensed physician ("Physician"). Also before you begin to follow any part of the Protocol, you need to receive full medical clearance from a Physician.

The United States Food and Drug Administration has not evaluated the contents of the Protocol.

Some of the supplement dosages and application methods contained in the Protocol may be different from those recommended by supplement manufacturers on their supplement bottles.

Nothing contained in Protocol is intended to create a physician-patient relationship with You must stop immediately and NOT follow the Protocol if you feel if you feel very faint, dizzy, sick or unwell at any time.

Ownership and Use

This Web Site and all content and materials included on this Web Site, including without limitation all information, text, graphics, illustrations, photos, video, sound and software (collectively the "Content"), are copyrighted and protected under U.S. and international copyright laws, trademark and other intellectual property laws and treaties and are the exclusive property of Dr. Michael Lam. Dr. Michael Lam hereby retains all right, title, and interest in the Content.

All rights are reserved. You may not store, modify, create derivative works of, translate, distribute, publish, transmit, sell or participate in any sale of, or exploit in any way any Content in any form or by any means. You acknowledge that you do not acquire any ownership rights by downloading material from this Web Site. You are authorized to view this Web Site for informational purposes only. No part of this Web Site or Content can be redistributed, copied, adapted or reproduced without the prior written consent of Dr. Michael Lam.

© 2005  Michael Lam, M.D. All Rights Reserved.

Questions? Ask Us Here

Questions? Ask Us Here

Adrenal Fatigue Test Adrenal Fatigue Test

Sign Up for the World's First Adrenal Fatigue Newsletter and Get A FREE 21 Page Whitepaper: Fatigued Out of Life.