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Fractures Caused By Diabetic Medication

Drugs which improve blood sugar control in diabetics may have another side affect. It may actually be harming the bones of women.

Researchers analyzed data from close to 14,000 people. Results showed that women who took a class of drugs known as thiazolidinediones were more likely to have reduced bone density in the lumbar, spine and hip sections compared to women who didn't take these drugs. This risk was not seen in men.

Thiazolinediones are taken by more than 4 million Americans. Half of these are likely to be women. Extrapolating from this, researchers believe that these drugs may be responsible for up to 30,000 bone fractures every year.

SOURCES: CMAJ, December 10, 2008

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