Cancer Risks Lower With Estrogen

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Hormone therapy, once thought to increase the risk of breast cancer, now shows promise in decreasing the risk of developing colorectal cancer.

Over 56,000 postmenopausal women had their data collected in the study. Results showed that there was a 45% decreased risk of developing colorectal cancer for women who had used estrogen plus progestin completely five or more years previously over women who had not taken the hormones before. Women currently on estrogen presented a 25 percent reduced risk. Women reported to have been taking estrogen for more than 10 years had a 26 percent reduced risk of developing colorectal cancer.

Previous research suggests that the hormones might have a role in reducing insulin-like growth factors. This might be an explanation for the reduced risk of cancer.

SOURCES: Cancer Epidemiology, Biomarkers and Prevention, 2009;18:196-203

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