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The FDA has just announced that a black box warning be put on topical steroids to inform physicians and parents that the use of these steroids for pediatric atopic dermatitis may lead to asymptomatic, secondary adrenal suppression. Adrenal suppression arises when a child experiences a traumatic situation that activates symptoms of acute adrenal insufficiency.
Symptoms of acute adrenal suppression include nausea, vomiting, hypotension, weakness, and fatigue. There are easily overlooked and assumed to be the result of trauma or infection. Children who have atopic dermatitis are usually prescribed topical steroids for treatment. The analysis is done by a cosyntropin stimulation test, in which a supra physiological dose of synthetic cortiocotropin is given intramuscularly or intravenously.
Therefore, experts warn of using topical steroids on children to avoid adrenal suppression.
Source: "Adrenal Suppression Often Overlooked in Topical Steroid Tx," Kubetin SK, Family Practice News.| Related Articles |
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