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Lung Cancer Gene Inherited

Lung Cancer is the number 1 type of cancer that kills in the United States. 200,000 lung cancer cases were diagnosed in USA in 2005, the most recent year for these statistics by the CDC.

New study shows that genetics play a role in having a higher risk for lung cancer. Those with a certain genetic variant have higher chances of developing the disease even with a small exposure to cigarette smoke. Even non-smokers who are exposed to second-hand smoke should be careful.

The study was conducted by the Genetic Epidemiology of Lung Cancer Consortium (GELCC) and showed strong gene-environment correlation between smoking and chromosome 6q. Those with the susceptibility locus can be stricken with lung cancer even with a little exposure to smoke. Those without the genetic locus had risks of developing the disease that followed closely to amount of smoking done. Carrying this inherited risk, or haplotype (the part of chromosome that contains the genes that are inherited together), greatly increased the chances of developing lung cancer.

Those with family histories of lung cancer should try to stay away from smoking, smokers, and smoke itself.

SOURCE: Genetic Epidemiology of Lung Cancer Consortium

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