Old female with severe liver clearance issues and severe fatigue

Q: I am a 61 year old female with severe liver clearance issues and severe fatigue much of the day. I can hardly hold my regular job as an administrative assistant. I feel exhausted at the end of the day. I feel toxic much of the time, especially if I am not careful with my diet. I had a blood test done recently by my doctor and my estrogen levels are high. My primary doctor wants me to lower my estrogen immediately. What can I do?

A: First of all, blood test for estrogen is not very accurate because it does not measure the free hormones that are active. What is measured is the total hormone, including the protein carrier. If that carrier protein is high, much of your estrogen can be sequestered and, therefore, not available to your cell. You can therefore have high serum levels of estrogen but cellular deficient. Because estrogen is metabolized by the liver, any liver dysfunction tends to increase circulating estrogen. When you have AF, progesterone level tends to go down, resulting in a condition known as estrogen dominance. As you can see, there are many factors to consider, and it is much complicated that meets the eye. First thing you should do is to ascertain whether you have too much estrogen or too little. Doing a saliva test for estrogen may be helpful, but the key is a good detail history. In a setting of Adrenal Fatigue, most people tend to have excessive estrogen, but you do not want to reduce it too quickly, as that may make things worse. Focusing your energy on healing your adrenals should be the primary step. As the adrenal heals, estrogen levels tend to normalize.