What is the effect of selenium and what does it contain?

Q: What is the effect of selenium and what does it contain? Also I have fibromyalgia and lung fibrosis. I am on Imuran. Is it safe for me to take the ATP boost, SAMe, Vitamin A, 5-HTP, Selenium, MSM, Milk Thistle combined? I read on the Internet that this helps fibromyalgia.

A: Selenium is a trace mineral and an antioxidant. It plays a vital role in the functioning of the antioxidant enzyme glutathione peroxidase. As such, it affects all components of the immune system, including the development of white blood cells. Selenium deficiency results in depressed immune function and a higher risk of infection. In one study, selenium supplementation of 200 mcg per day to people with normal selenium levels in their blood leads to 118 percent increase in the ability of the lymphocytes to kill tumor cells and 82.3 percent increase in the activity of natural killer cells. Unfortunately, dietary intake is often insufficient, although high amounts are found in Brazilian nuts if you are a nut lover.
Fibromyalgia is a common cause of musculoskeletal pain and fatigue. It is often associated with chronic fatigue syndrome. The central cause of the pain of fibromyalgia appears to be a low level of serotonin.
Imuran is an immuosuppressive medication commonly used to reduce the body’s natural immunity in patients who receive organ transplants. It is also used to treat rheumatoid arthritis and other conditions your physician feels indicated. Imuran can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting.
Milk Thistle is an herb with liver protection properties. It prevents damage to the liver by acting as an antioxidant as this protective effect has been demonstrated in a number of studies. It is used widely by people who have hepatitis from causes such as alcohol.
If your intention is to boost your immunity function, then Selenium, Milk Thistle, Vitamin C, and Vitamin E are all supplements worth considering.
If your intention is to get relief from your fibromyalgia, many have reported improvement with Magnesium and Malic Acid in conjunction with a high potency multivitamin and mineral formula. 5-HTP may be effective on its own due to its conversion to serotonin, although magnesium in combination with Malic acid and calming herbs such as Kava Kava or St. John’s Wort may be better due to its synergistic effect.
In addition, you should watch your diet to eat more fruits and vegetables, stay away from saturated animal fat, and reduce your stress level.
Without knowing what bothers you the most, the above will give you a general direction of how to proceed.