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This Week's Case Study

The Case

I read an excerpt from your web page on adrenal insufficiency. I am a senior year biochem student and I would like to do research in the area of endocrinology. I wanted to know your thoughts on how to best restore proper adrenal function - especially when excess androgens are produced due to alternate pathway. Do you think that it is best to utilize pregnenolone solely or would you use this in conjunction with progesterone and natural hydrocortisone. DHEA would be less preferable since symptoms of hyperandrogenism are often present (hirsutism, scalp hair loss, acne, etc..). I have noticed in women that this is often the symptom presentation associated with adrenal insufficiency. I appreciate any thoughts that you might have.

My Answer:

Burning fat as a fuel source is always better than burning glucose. Most of us through the years have trained our body to burn glucose, and thus the body breakdown with resulting diabetes, lipid abnormalities, just to name a few. Sugar addiction takes 2-3 years to overcome for most, and I encourage sugar balancing to help in this respect. Aside from controlling sugar balance, changing the body's fuel source from sugar to fat should be the ultimate aim (good fat, mind you) provided that the body of the person is metabolically typed to accept fat as the source. Many people do well on complex carbo as primary source of fuel and will do poorly on fat as well, especially those of Type B blood and relaxed personality (type B personality). This is in contrast to Type O blood type and Type A personality who do well on high good fat (monounsaturated fat such as olive oil for non-high heat use, and coconut oil (saturated fat) for high heat use.

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