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Sugar and Aging


Michael Lam, MD, MPH
www.DrLam.com

(READING TIPS:  For fast reading, scan through the topic headings in BOLD BLACK, important conclusions in BOLD BLUE, and " Must Know " in BOLD RED. To jump to specific sections in this article, click on the respective LINKS in the Contents.

Before You Begin

Information presented here is for general educational purposes only. Each one of us is biochemically and metabolically different. If you have a specific health concern and wish my personalized nutritional recommendation, write to me by clicking here.

Contents
Introduction
Sugar in the Body and Diet
Sugar vs. Carbohydrates
Starch vs. Carbohydrate
Carbohydrate Breakdown and Storage
How Much Carbohydrate and Food Energy Is Needed?
Classification of Carbohydrates
A. Simple versus Complex Carbohydrates
B. Paleocarbs vs. Neocarbs
C. High vs. Low Glycemic Index Foods
What is "Normal" Blood Sugar Level?
Effects of High Blood Sugar
A. Increase in Diabetes
B. Increase in Cancer
C. Increase in Free Radicals and Reduced Antioxidants
D. Increase AGEs
E. Increase in Heart Disease
What You Should Do

 

Introduction


Common table sugar represents about 20 to 25 percent of the daily caloric intake of the average American. This translates into the equivalent of half a pound a day and over 5 tons in a lifetime. In the early 1800's, the average sugar consumption was 12 pounds per person annually. This increased to 124 pounds in 1980 and to 152 pounds in 1997. It is estimated that 75 percent of all sugar we consume comes from processed food
.

Studies have linked a high sugar intake with an increased risk of diabetes, cardiovascular disease, cancer, and premature aging. Is this pure coincidence, or is the association real?

Sugar in the Body and Diet

Sugar is a generic term used to identify simple forms of carbohydrates, which includes fructose, glucose, galactose, maltose and sucrose (white table sugar). The type of sugar and its rate of breakdown can affect the body greatly. For example, table sugar (sucrose) is considered nutritive as it contains calories, although it does not contain vitamins, minerals or fiber. Another sugar type known as glucose has the ability to break down quickly in the stomach and later be pumped across the intestinal wall directly into the bloodstream. This process rapidly raises blood-glucose levels, which causes the blood sugar level to spike. On the other hand, fructose, which is sugar derived from fruits, gets into the body and is slowly absorbed in the gut. It is then converted to glucose in the liver. This makes fructose a "time-release food" as it delivers calories at a gradual rate. A complete understanding of sugars and how they affect our body is critical to the study of how sugar influences aging.

Sugar vs. Carbohydrates

Carbohydrates are merely different forms of sugars linked together in polymers. Most people will consider sweets and pasta as carbohydrates. Most are not aware that fruits and vegetables are also considered carbohydrates as well. In reality, sugar, sweets, pasta, vegetables and fruits are all carbohydrates.

This confusion is compounded when one considers that a carbohydrate diet consisting mainly of green leafy vegetables is good for anti-aging. On the other hand, a carbohydrate diet consisting primarily of white rice, potato, pasta, cakes, ice cream, and bread is a negative fountain of youth.

While both “good?and “bad?carbohydrates are classified in the same general group, the effects on the body are totally different. To put matters into proper prospective, any discussion on carbohydrates must clearly address the specific kinds of carbohydrates in question.

Starch vs. Carbohydrate

Starches are the most basic form of carbohydrates. It is found in all fruits, vegetables, grains and legumes. Starch is broken down in our digestive tract into small molecules of glucose, which are then absorbed and transported into cells for energy production.

Many fruits and some vegetables contain significant amounts of glucose and fructose, as well as a disaccharide called sucrose (ordinary sugar), which contains both glucose and fructose.

Our bodies have been accustomed to metabolizing about 300 grams of glucose (mostly from starchy foods) every day for thousands of years.

We have always consumed some fructose, often in the form of fruits and honey. Until about 200 years ago, the average daily intake of fructose was only eight grams a day. As ordinary sugar (sucrose) from sugar beets and sugar cane began to be readily available, the daily intake of fructose raised 10 fold to 75 grams a day. The problem is further compounded since the 1970s, when high fructose corn syrup was introduced as a substitute sweetener. About 9% of the average dietary calorie intake now comes from fructose.

When sucrose is ingested, it reacts with water to generate glucose and fructose in equal amounts. Each 100 grams of sucrose produces 53 grams of glucose and 53 grams of fructose. Sucrose is called a disaccharide for this reason. The ingestion of 100 pounds of sugar (sucrose) per year translates into 125 grams per day and 66 grams of fructose. With about 8 grams added on from fruits and honey, the total average intake per day now becomes 74 grams. Our body is used to metabolizing only eight grams of fructose a day. The nearly 10-fold overload has caused many health problems, which we will discuss below.

Carbohydrate Breakdown and Storage

Carbohydrates break down into glucose, which is the primary fuel the body needs to keep it operationally functional. Certain organs require more fuel than others to run. The brain utilizes almost two thirds of the circulating carbohydrates in the bloodstream to keep it functioning.

Any excess carbohydrates not needed are stored as glycogen (a storage form of glucose). Glycogen is stored in the liver and the muscles. When the brain needs fuel, the glycogen in the liver is broken down and transported to the brain for energy.

How much carbohydrate can you store? The total storage capacity of the body for carbohydrates is limited. An average person stores about 300 to 400 grams of carbohydrates in the muscles, which cannot be utilized by the brain for energy. Only 60 to 90 grams are stored in the liver for glucose conversion, equivalent to about two cups of cooked pasta or three typical candy bars. This is all the body has in reserve to keep the brain working properly.

Once the glycogen levels are filled in both the liver and the muscles, excess carbohydrates are converted into fat and stored in the adipose tissue. Hence, excess carbohydrates become fat. In modern day society, it is sugar that makes a person fat much more that the amount of fat a person consumes.

How Much Carbohydrate and Food Energy Is Needed?

The key function of carbohydrates is to provide energy for the body. Julius Robert Mayer, a German physician, initially discovered the concept of food energy in 1842. The energy values of a food can be determined by burning a set amount of food and measuring the amount of heat produced. The common energy value is expressed in kilocalorie and is based on the burning of 100 grams (or 3.5 ounces) of the food. It is determined that approximately 900 kcal is generated per 100 gram of fat and 400 kcal per 100 gram of carbohydrate and protein intake.

There are only four macronutrients we consume on a daily basis - water, fat, protein, and carbohydrates. Out of these, only carbohydrates are nonessential to the human diet. One can survive for long periods of time without carbohydrates provided that protein and fat needs are met, for these two are ultimately broken down to form building blocks of carbohydrates as food energy for the body.

An intake of 300 grams of carbohydrates yielding 1,200 kcal would provide 50 percent of an average daily requirement of energy in an average American diet. A 2,500-calorie diet with 20 percent of energy provided by protein (about four ounces or 120 grams) will generate about 500 calories of energy. The amount of protein needed to sustain normal bodily function can be readily supplied in four ounces of meat. The average American consumes more protein than is needed.

 

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