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Acidosis

Michael Lam, MD, MPH
www.DrLam.com

(READING TIPS:  For fast reading, scan through the topic headings in BOLD BLACK, important conclusions in BOLD BLUE, and " Must Know " in BOLD RED. To jump to specific sections in this article, click on the respective LINKS

Before You Begin

Information presented here is for general educational purposes only. Each one of us is biochemically and metabolically different. If you have a specific health concern and wish my personalized nutritional recommendation, write to me by clicking here.

Contents
pH
Acidosis
The Principal Sources Of Acid Buildup
The Effects Of Acidosis
Diseases Associated With Acidosis
How Does The Body Overcome The Acidity
Associated Metabolic Effects
How To Test Your pH Level
Food Plan To Reduce Acid
Acid Producing Foods
Alkaline Producing Foods


One of the key determinants of the speed of aging and onset of degenerative diseases is the internal biochemistry and terrain of the body.

Internal biochemistry is best measured and discussed in terms of the pH. pH is a measurement of the amount of acid and base. It ranges from 1 to 14, with 1 being extremely acidic, and 14 being extremely basic. A neutral state has a pH of 7. The term acidosis is relative and only meant to convey a shift in total body chemistry towards the acidic direction.


pH

According to the research of Dr Enderlein, our bodies can only be healed of any chronic illness when our blood is at a normal, slightly alkaline pH.

What exactly does pH mean? pH is the short form for potential hydrogen. The pH of any solution is the measure of its hydrogen-ion concentration. The higher the pH reading, the more alkaline and oxygen rich the fluid is. The lower the pH reading, the more acidic and oxygen deprived the fluid is. The pH ranges from 0 to 14, with 7.0 being neutral. Indicator above 7.0 is alkaline and below 7.0 is considered acidic.


Our blood pH has a very narrow range of around 7.35 to 7.45. If our body's pH deviates from this range, we will be sick or have symptoms of falling sick. If our blood pH falls below 6.8 or above 7.8, our body cells will stop functioning and death will occur.

A normal healthy body will have an almost equal blood pH of acidity and alkalinity. The most ideal pH balance is 7.4 , which means that it is slightly more alkaline than acid. Only when the pH level is balance that our bodies can then effectively assimilate vitamins, minerals and food supplements. As such, our body pH's determines everything.

An acid pH body is more prone to illness. In an acidic environment, red blood cells cannot repel and stick together like a stack of coins, forming what is called rouleau formation. This formation limits the amount of oxygen carrying capacity because red blood cells sandwiched between the two ends are compressed against each other and therefore unable to carry oxygen. Reduced oxygen leads fatigue, lack of energy, and weakness, just to mention a few symptoms. Furthermore, cancer cells strives in an oxygen deprived environment (anaerobic) much better than in an oxygen rich environment.
The importance of maintaining optimum pH is therefore a critical factor in balancing proper internal terrain to deter cancer, infection, and a host of inflammatory disease. The majority of these conditions worsen in an acidic environment. They do not do well in an acidic environment.

The normal human cell is slightly alkaline and has an abundance of molecular oxygen. The cancer cell is acidic and cannot survive in an oxygen rich environment. As such, we can conclude that pH balance is very important to one's health, especially for the cancer patient.

The pH indicators are an exponent number of 10. A small difference in pH will translate to a big difference in the number of oxygen or OH-ions. A difference of 1 in a pH value means ten times the difference in the number of OH-ions. A difference of 2 means one hundred times the difference in the number of OH-ions. In other words, a blood with a pH value of 7.45 contains 64.9% more oxygen than blood with a pH value of 7.30.


Acidosis

Acidosis is a pH imbalance where the body has accumulated too much acid and does not have sufficient acid neutralizer to neutralize the effects. Acidosis may result from a lack of insulin, a starvation diet or even a gastrointestinal disorder like vomiting and diarrhea.

The acidic biochemical type is not meant to represent the absolute pH measurement of the blood system, which generally requires a laboratory test performed in hospitals known as blood gases. While certain areas of the body normally may have an more acidic environment (stomach, kidneys, bladder) than others, the overall pH of the body and blood normally must be maintained within a narrow range of alkalinity (pH 7.30 - 7.45. An absolute blood measurement of acidity (pH below 7.0) is incompatible with life. 


The principal sources of acid buildup are:

1.) The metabolism and/or incomplete breakdown (oxidation) of foodstuffs or metabolic "waste" produced as a by-product of cellular activity. During normal cellular respiration and energy production , acids as produced as part or "waste" products. These acid must be "balanced", neutralized, or removed by the body's buffering and detoxification systems through the kidneys, lungs, liver, and blood.

2.) The consumption of acid present in the food, air, and water supply. Nitrogen emissions from automobiles and industrial plants, food dyes, sprays, waxes, preservatives, additives, artificial sweeteners, fertilizers, water pollutants, and even chloride and fluoride in tap water are just some of the highly acidic chemicals are ingested by millions everyday.


THE EFFECTS OF ACIDOSIS

Acidosis leads to serious problems with major organs such as the liver, heart or kidneys. In this article, we will be looking into some of the reasons as to why we should avoid acidosis.

1.)  It corrodes arteries, veins, and heart tissues

Like acid eating into marble, acidosis erodes and eats into cell wall membranes of the heart, arteries and veins. During this process of erosion, our heart structures and inter connective tissues are weakened.

All living tissues are sensitive to their chemical environment. The muscle cells of the heart are no different. The entire cardiovascular system is directly affected by blood plasma pH and works as one large working "system of tubular muscles" to carry blood and nutrients to all living tissue in the body. The pumping of the heart drives blood through the arteries, veins and capillary beds and helps to regulate blood pressure and the flow of blood circulation.

The heart is normal when the pH of blood plasma is slightly alkaline, having a pH of 7.35 to 7.41. When the heart plasma rises to an acidic pH of more than 7.35, it gradually erodes away the smooth muscle tissues of the inner walls of the arteries and veins, as well as the heart itself. This process will start to weaken the structural composition of the heart, arterial and venous walls, causing lesions and microscopic tearing throughout its framework. At the same time, an acid pH destabilizes free ionic balances within circulation, increasing the populations of positively charges particles (cations, an ion with a positive charge of electricity: H , Ca ) which directly interfere with the muscle contractility (contraction and relaxation) of the heart and arteries.

Acid pH changes of blood are now thought to result in the following: -

A. Development of arteriosclerosis (hardening of the arteries)
B. Aneurysm (widening and ballooning of artery walls)
C. Arrthythmias (abnormal rhythms of the heart including tachycardia)
D. Myocardial infarction (heart attacks)
E. Strokes (a cardiovascular accident).

The structural weakening of the cardiocascularity also creates irregularities of blood pressure, which further exacerbates the above problems.

2.)  It accelerates free-radical damage and premature aging.

Acidosis leads to partial lipid breakdown and destructive oxidative cascades accelerating free radical damage of cell walls and intracellular membrane structures. In this process, many healthy cells are destroyed.

Acidosis is the first step towards premature aging and accelerated oxidative cascades of cell wall destruction. Signs of acidosis may include wrinkling, age spots, failing hormonal systems, interfering with eyesight, memory, and a host of other age-related phenomena. Unwanted wastes not properly eliminated from the body actually poison the cells.

3.)  It disrupts lipid and fatty acid metabolism.

Acidosis generally disrupts lipid and fatty acid, which are involved in nerve and brain function. This disruption causes neurological problems such as MS, MD as well as problems with hormonal balance within the endocrine system.

An acidic environment also causes LDL-cholesterol to be laid down at an accelerated rate in the heart, inappropriately lining and clogging up the vascular network. In other words, an acid pH initiates electrostatic potential, damaging arterial walls, which in turn initiates a PDGF-dependent immune response, causing cholesterol oxidation and the formation of plaque with heavy metals.

4.) It leads to weight gain and  diabetes.

An acidic pH may result in weight problems such as diabetes and obesity. When our body is too acidic, we suffer from a condition known as Insulin Sensitivity. This forces excessive insulin to be produced. As a result, the body is flooded with so much insulin that it diligently converts every calorie into fat.

It is very likely that an acid pH, from an imbalanced diet, produces a condition, which stimulates the predetermined genetic response to starvation and famine. Thereafter, the body will have to increasingly hoard every calorie consumed and store it as fat.

Some people reckon that an acid pH immediately signals the powerful genetic response to an impending famine, directly interpreting with the all important and very sensitive Insulin-Glucagon Axis. When this happens, it makes the body produce more insulin than usual, and in turn, produce more fats and store it.

On the other hand, a healthy and slightly alkaline pH will yield normal fat burning metabolic activities, making no demands on the body to produce extra insulin and make fats. As such, this allows fat to be burned and naturally lost. A healthy pH diet is also less likely to have any yo-yo effects, or rebounding from a diet with additional weight gain. We should try to maintain a healthy slightly alkaline pH so as to allow fats to be burnt normally for energy, rather than hoarded and stored under the mistaken biochemical belief of an impending famine.

Acidosis also disrupts the insulin producing pancreatic beta cells. These beta cells are especially sensitive to pH and cannot survive if the body is too acidic. When this occurs, beta cells will lose phase with one another. Their cellular communication will be thwarted and the body's immune system will start to over-respond. Stress within the cells will increase, making them more difficult to perform adequately and survive.

5.) It alters the energy metabolism and reserve.

When your body has an acidic pH, it will prevent efficient cellular and body metabolism. Acidosis results in chemical ionic disturbances, interfering with cellular communications and functions. Acidosis reduces plus calcium binding of plasma proteins, therefore reducing the effectiveness of this intracellular signal. It also results in a disease of calcium cations (positive calcium) entry through positive calcium channels. This leads to a reduction of cardiac contractibility, or the ability of the heart to pump efficiently and rhythmically.

Positive calcium and hydrogen regulate the activities of intracellular proteins and are driven out of the cells by the "Sodium-Potassium pump" (Na-K pump). This pump provides a strong incentive for sodium to be driven into cells. It also regulates the amount of both sodium and potassium in the body stores, and uses as much as 25 percent of our caloric input daily. Positive calcium exchanges the plus sodium, being forced out of cells, but naturally, the electrochemical gradient for positive calcium favors both positive hydrogen and positive calcium entry into cells, as there is less calcium and positive hydrogen in cells than in the extra-cellular fluids. In extra-cellular fluids, there is 10 times more the amount of positive sodium.

In acidic solutions, less plus sodium is available, therefore slowing down the processing and induction of nutritional items going into the cells. This increases positive hydrogen and calcium buildup within the plasma, making it more available to electro-statically bind with LDL-Cholesterol. As a result, with free positive calcium populations and channels being disrupted, calcium may become inordinately leached from the bone masses. This causes osteoporosis. In a nutshell, an acidic pH drains us of energy and disallows stored energy reserves to be used.

6.) It slow the delivery of oxygen into the cell.

Acidosis reduces oxygen in the blood. As all living tissues, especially the heart and brain need oxygen to function; a lack of it will lead to eventual death.
Having an acidic pH will reduce the amount of oxygen that is delivered to the cells. They will eventually die.


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